PHYTOCHEMICAL ANALYSIS AND THE ANTI- INFLAMMATORY ACTIVITIES OF METHANOL EXTRACT OF CRATEVA ADANSONII

Inflammation  is  a  complex  biological  response  of vascular  tissue  to harmful  stimuli  such as  pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated  anti-inflammatory  drug research over the last  decade  while  synthetic  pharmaceutical  agents continued to dominate research, attention increasingly has been directed to natural products. These are often more  affordable  and  available  and  sometimes  are perceived  as  more  effective  than  conventional  anti- inflammatory drugs.

Anti-inflammation was carried out using 11 rats. That was divided into three groups of four rats each. Group 1 and  2  served  as  the  positive  and  negative  control respectively. Groups 3 and 4 received 200mg/kg b.w and  600mg/kg  b.w.  of  the  extracts  respectively. However,  it  was  discovered  that  the  stem  bark  of
crateva  Adansonii     showed  greater  significance  anti-
inflammatory activity when compared with the standard. 

Bsu 2017/2018 Post UTME Form and Admission Screening Date

Bsu 2017/2018 Post UTME form is out. The form costs N2500. Candidates who chose Bsu as first or second choice in the 2017 Jamb examination and had a score of 180 and above can apply. Registration will begin on Tuesday, 12th September, 2017. The deadline for applying is Thursday, 21st September, 2017. All candidates who applied for Law but scored between 180 and 199 are to take their PUTME in Faculty of Arts, while candidates who applied for Medicine and Surgery but scored between 180 and 199 are to take their PUTME along with Anatomy, Physiology and Faculty of Science. The date for the Post UTME exercise shall be communicated to candidates after registration.

To apply, follow the instructions below:
1. Go to http://bsum.edu.ng
2. Click on E-Payment to open the E-Payment page
3. Select Programme, Payment category as "POST UTME APPLICATION"
4. Type in the UTME Registration number,
5. Select Session as “2017/2018”
6. Select “Session” under semester field
7. Click on “Generate payment reference” button to generate reference number
8. Click on “click to proceed” link at the bottom of the page to access four payment options as follows:
a. For On-line payments using Mastercard, VISA and Verve Cards, click on the “Pay Online” button. You will be taken to Interswitch Payment Page. From the drop down below the page, select you card type and enter the requested information to make Payment. Once your payment is completed successfully, a receipt will be issued and you can continue with your application.
b. For cash payments at Bank, print your Payment Reference Number slip from the E-Payment Platform and take it to either Fidelity Bank Plc; Zenith Bank Plc; ECO Bank Plc; Guaranty Trust Bank Plc; Sterling Bank Plc; Diamond Bank Plc; First Bank of Nigeria Plc; United Bank for Africa Plc; Unity Bank Plc; Union Bank of Nigeria Plc; or Skye Bank Plc. On receipt of cash from you, the Bank using “College Pay” will process your transaction and generate Payment Receipt for you.
c. For payment at ATM terminals, visit any ATM terminal with your ATM card and Select Quickteller from the ATM menu; select pay bills; fill in the Payment reference Number generated from the E-Payment platform when you are requested to enter the Customer ID; fill in 04255101 when you are requested to enter the Payment Code; enter your GSM Number and complete the transaction. After successfully completing the payment, return to the portal to login and print out your Payment Receipt.
d. For payment using Quickteller from the Internet, go to http://bit.ly/2cNtlxM while applicants for courses in the College of Health Sciences should visit http://bit.ly/2wc3it4 to complete their transaction. Enter your Registration number. Enter your email and mobile number and click "continue". Follow the instructions on the screen to complete your payment. Print out the payment confirmation slip. Return to the portal and print out a payment receipt. Note that this payment option attracts additional N100.
10. After payment, candidates are expected to revisit the University website http://bsum.edu.ng and now select “Post UTME/DE” under “Applications” on the “Portal” section left of the University website. Once on the page, candidates are to follow the steps below to complete their registration:
a. Enter your UTME Registration number and click “Verify” button to log in. Register and upload credentials online for the Post-UTME exercise.
b. Click on “My Bio Data” link to complete your Biodata.
c. Click on “Upload Documents” link to upload the following documents:
i. WAEC/NECO/NABTEB Certificates or statement of results (not online slips).
ii. Birth Certificate/Declaration of age.
iii. Marriage certificate/affidavits.
iv. Certificate of State Origin.
v. JAMB Result slip.
d. Click on “Acknowledgement Slip” link to print and submit to Faculty Officer of your faculty for signing and documentation.

Candidates are expected to present the Acknowledgement Slip on day of Post UTME. If you will like us to send you a text message whenever there is a news relating to Bsu 2017/2018 Post UTME Admission, enter your mobile number below and click Subscribe and we will send you a text message for upcoming news like:

Federal Polytechnic Nasarawa CBT Test 2017/2018 Academic Session

Dear applicant you are hereby invited to come for a CBT Screening Exercise for the 2017/2018 Academic Session. This round of the screening is for Full-time HND, Part-time HND, & PreHND applicants only. Upon arrival you will be required to pay two thousand naira (N2000.00) only to sit for the screening test. The day for your test is itemized below:

 

1. School of Information Technology – Monday, 18 September 2017
2. School Applied Science – Tuesday, 19th September 2017
3. School of Environmental Studies – Wednesday, 20th September 2017
4. School of Engineering Technology – Thursday, 21st September 2017
5. School of Business Studies – Friday, 22nd September 2017
6. School of Vocational & Continue Education – Saturday, 23rd September 2017
Time: 7:00 am prompt every test day
Venue: PTDF ICT Center, Main Campus, The Federal Polytechnic, Nasarawa.
For more information please contact: Mr Usman Faruna on +2347036191417 or Mr Baba Dangana on +234 703 182 7656

ELEMENTAL ANALYSIS ON PTEROCARPUS MILDBREADII (OHA)SEED

Elemental analysis is the qualitative detection and quantitative determination of chemical  elements(atoms,ions)in  a  sample(Fritz  Pregl    1923).  To  detect  an element, one should fix an appearance of an analytical signal. The formation of precipitate  or  characteristic  crystals,  colour  change,  an  isolation  of  gaseous products, an appearance of a definite lines in spectrum, luminescence, etc. To determine elements quantity, it is necessary to  measure a value of an analytical signal; a precipitate mass, intensity of a current, solution absorption, spectrum line,
luminescence or radioactivity, a reaction rate and so on.(    www.intechopen.com    ).
This study was undertaken to analse the elements present in grounded Pterocarpus mildbreadii (Oha seed) using Atomic Absorption Spectrometer(AAS MODEL- AA320N).The seed was found to contain these essential macro minerals/elements sodium(Na),Potassium(K),calcium(Ca),magnesium(Mg),and  the  trace  elements iron(Fe),copper(Cu),zinc(Zn), and selenium(Se)(Duffus,2002).
 The study established that Pterocarpus mildbreadii(oha seed) does not contain manganese and has high content of potassium which is necessary for good health.

DETERMINATION OF ACTIVE SWEET COMPONENTS OF COMMON ARTIFICIAL SWEETENERS THAT ARE USED AS REPLACEMENT FOR SUGAR

This research investigated how the sweetness of sugar substitute compares to the sweetness of sugar. In this research different percentage solution of sugar, artificial sweetener and natural sweetener (10%, 1%, 0.1% and 0.01%) were prepared. Ten volunteers were gathered for the sensory evaluation in this case tasting of the solution, the volunteer?s taste threshold of data was gotten. The artificial sweetener was found out to be the sweetest among the substances experimented and at the percentage of 0.1% and 0.01% saccharin an artificial sweetener was able to mimic the taste of sugar. Research prove that artificial sweetener are non-nutritive they have virtually no calories in contrast to sugar which contains 4 calories at each gram, a teaspoon of sugar is about 4 grams, for weight lose artificial sweetener may be an attractive option to sugar. Artificial sweetener may also be a good alternative for diabetic patient, unlike sugar; artificial sweeteners generally don?t raise blood sugar levels because they are not carbohydrates.

THE EFFECT OF ETHANOL EXTRACT OF DESMODIUM VELUTINUM STEM ON SOME MARKER EMZYME IN LIVER OF ALBINO WISTAR RATS

Present  investigations  were  carried  out  on  the  effect  of  ethanol  extract  of Desmodium velutinum     stem on some liver enzymes of albino wistar rats fed with high fat from cow?s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower?s mash) and tap water. Group II rats were fed with fat diet (cow?s brain) (3.6g/day) alone. Group III rats received combined mixture of 70% fat diet (cow?s brain) with  ethanol extract of Desmoduim elutinum stem (2.7g/day), Group IV rats were fed with fat diet (cow?s brain) and were administered with a drug atorvastatin (5mg/rat/day). The rats were sacrificed at the end of the experimental (two weeks) period. The plant extract  was screened for its phytochemical constituents, using standard procedures.

Phytochemical screening revealed the presence of tannins, flavonoids,  saponins  and  alkaloids.  The  liver  function  tests  was  assessed  by measuring the total bilirubin, total serum protein, direct and indirect bilirubin and liver  enzymes  such  as  Alanine  amino  transferase  (ALT),  Aspartate  amino transferase (AST), Alkaline phosphate (ALP), Gamma-glutamyl transferase (GGT) on the liver of the albino wistar rat. The serum, ALT, ALP, AST and bilirubin concentration of the albino wistar rat increased significantly (P>0.05) compared to their total protein concentration. The result obtained indicate that the ethanol extract of     Desmodium Velutinum     stem possess hepatoprotective activity on the fatty liver of albino wistar rat fed with fat from cow?s brain. The studied plant showed variable amount of phytochemicals including flavonoid, alkaloid, saponin, tannins, terpenoid  which  were  determined  quantitatively  using  literature  methods.  The  significant effect of the     Desmodium velutinum     stem  ethanol extract was compared with standard drug, atorvastatin. The result in the present study suggest that the ethanol extract of  Desmodium velutinum     stem can be used in treating liver diseases. 

THE EFFECT OF PTEROCARPUS MILDBREADII SEED ON PLASMA HDL CHOLESTEROL OF ALBINO RAT

This work was carried out to investigate the effects of pterocarpus mildbreadii seed on the HDL- level of albino rats.High density lipoprotein(HDL) is a fraction of cholesterol,which helps to transport cholesterol from peripheral of cell to the liver.High density lipoprotein is carried out to investigate cardio vascular diseases.Fresh oha seed (pterocarpus mildbreadii seed) was collected from Amokwe in udi local government  Area Enugu state .

They were dried at room temperature for about a month in an open laboratory space, groud into coarse form and weighed on an electrical weighing balance. 3% tween-80 was prepared by dissolving 3%  tween -80 in 97ml of distilled water. The grounded pterocarpus mildbreadii was dissolve in the 3% tween-80.A total of sixteen wistar abino rats used for this analysis. The rats were divided into 4(four) groups. Group 1contain 4 rats and received 0.5  each of 3% tween-80. Group 2 contain 5 rats and were administered with 1400mg/kg b.w of pteridocarpus mildreadii solution Group 3 contain 3 rats and were administered  with 2600mg/kg. b.w of pteridocarpus mildbreadii solution. Group 4 contain 4 rats and were administered with 500mg/kg. b.w. of Edmard MRT complex.